2024
A comparison of machine learning methods for quantifying self-grooming behavior in mice
Correia K, Walker R, Pittenger C, Fields C. A comparison of machine learning methods for quantifying self-grooming behavior in mice. Frontiers In Behavioral Neuroscience 2024, 18: 1340357. PMID: 38347909, PMCID: PMC10859524, DOI: 10.3389/fnbeh.2024.1340357.Peer-Reviewed Original ResearchGrooming durationGrooming boutsRepetitive self-groomingSelf-grooming behaviorBehavior of miceTreatment conditionsLevels of groomingHigh-throughput pipelineBehavioral neuroscienceRestraint treatmentManual scoringSelf-groomingGrooming behaviorHomeCageScanOverestimate durationGroomingBehavior analysisDuration measurementsBehavior quantificationBehavior analysis toolMouse background
2023
Species-specific protein–protein interactions govern the humanization of the 20S proteasome in yeast
Sultana S, Abdullah M, Li J, Hochstrasser M, Kachroo A. Species-specific protein–protein interactions govern the humanization of the 20S proteasome in yeast. Genetics 2023, 225: iyad117. PMID: 37364278, PMCID: PMC10471208, DOI: 10.1093/genetics/iyad117.Peer-Reviewed Original ResearchConceptsProtein-protein interactionsYeast proteasomeLocal protein-protein interactionsSpecific protein-protein interactionsYeast proteasome subunitsVast evolutionary distancesC-terminal tailFull-length tailThousands of genesHigh-throughput pipelineYeast counterpartEvolutionary divergenceEvolutionary distanceAssembly intermediatesHuman genesProteasome subunitsComplementationProteasomeSubunitsYeastGenesDistinct interactionsCore assemblyHuman β3Β3 subunit
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