Two CD1 genes map to the chicken MHC, indicating that CD1 genes are ancient and likely to have been present in the primordial MHC
Salomonsen J, Sørensen M, Marston D, Rogers S, Collen T, van Hateren A, Smith A, Beal R, Skjødt K, Kaufman J. Two CD1 genes map to the chicken MHC, indicating that CD1 genes are ancient and likely to have been present in the primordial MHC. Proceedings Of The National Academy Of Sciences Of The United States Of America 2005, 102: 8668-8673. PMID: 15939887, PMCID: PMC1150808, DOI: 10.1073/pnas.0409213102.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsAntigens, CD1Base SequenceBlotting, SouthernChickensChromosome MappingCloning, MolecularCluster AnalysisComputational BiologyDNA PrimersDNA, ComplementaryEvolution, MolecularFlow CytometryMajor Histocompatibility ComplexMolecular Sequence DataPhylogenySequence Analysis, DNAConceptsCD1 genesChicken MHCCD1 systemPrimordial MHCDraft chicken genome sequenceChicken genome sequenceAncestor of mammalsClassical class I genesClass I genesGenome sequenceTranscriptional orientationCD1 isotypesPhylogenetic analysisSequence analysisI geneCD1 moleculesBackcross familiesSouthern blottingIntracellular vesiclesChicken linesII genesGenesSequenceRNA expressionNKT cells
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