Rapid progression to AML in a patient with germline GATA2 mutation and acquired NRAS Q61K mutation
McReynolds L, Zhang Y, Yang Y, Tang J, Mulé M, Hsu A, Townsley D, West R, Zhu J, Hickstein D, Holland S, Calvo K, Hourigan C. Rapid progression to AML in a patient with germline GATA2 mutation and acquired NRAS Q61K mutation. Leukemia Research Reports 2019, 12: 100176. PMID: 31245276, PMCID: PMC6582196, DOI: 10.1016/j.lrr.2019.100176.Peer-Reviewed Original ResearchAcute myeloid leukemiaMyelodysplastic syndromeProgression to acute myeloid leukemiaNRAS Q61K mutationDevelopment of acute myeloid leukemiaGATA2 deficiency syndromeGermline GATA2 mutationsQ61K mutationBone marrow failureHeterozygous germline mutationsTargeted deep sequencingGATA2 mutationsAllogeneic transplantationMarrow failureMyeloid leukemiaAML developmentBone marrowDeficiency syndromeHematologic abnormalitiesGermline mutationsK mutationWhole exomePatientsDeep sequencingMutations
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply