Viral Evolution Shaped by Host Proteostasis Networks
Yoon J, Patrick J, Ogbunugafor C, Shoulders M. Viral Evolution Shaped by Host Proteostasis Networks. Annual Review Of Virology 2023, 10: 77-98. PMID: 37071930, PMCID: PMC10543606, DOI: 10.1146/annurev-virology-100220-112120.Peer-Reviewed Original ResearchConceptsProteostasis networkViral evolutionProtein foldingViral proteinsRegulate protein foldingViral protein productionEffective antiviral strategiesProteostasis factorsShape viral evolutionHost machineryAdaptive mutationsProtein biophysicsProtein productionFolding defectsAntiviral strategiesSequence spaceProteostasisProteinHostFoldingQuality control processChaperoneBiophysical defectsMutationsSequence
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