2025
High Phosphate and Low Protein Mediate Arterial and Cutaneous Vascular Calcification in CKD Mice.
Jin Y, Cao F, Xie Y, Davis S, Dong G, Nigwekar S, Hansen J, Guzman R, Cai Y. High Phosphate and Low Protein Mediate Arterial and Cutaneous Vascular Calcification in CKD Mice. Journal Of The American Society Of Nephrology 2025 PMID: 40960881, PMCID: PMC12448113, DOI: 10.1681/asn.0000000875.Peer-Reviewed Original ResearchChronic kidney diseaseChronic kidney disease miceCutaneous vascular calcificationArteriolar calcificationVascular calcificationP38 MAPK signalingMedial arterial calcificationPharmacological inhibition of p38 MAPK signalingArtery calcificationLow-protein dietPharmacological inhibitionMedial arteryInhibition of p38 MAPK signalingCKD mouse modelMolecular pathwaysMAPK signalingExperimental CKD modelsPharmacological inhibitor SB203580Kidney impairmentAlizarin red stainingNephrectomy miceSignaling in vivoVascular complicationsKidney dysfunctionTreatment strategies
2017
An engineered cell-imprinted substrate directs osteogenic differentiation in stem cells
Kamguyan K, Katbab A, Mahmoudi M, Thormann E, Zajforoushan Moghaddam S, Moradi L, Bonakdar S. An engineered cell-imprinted substrate directs osteogenic differentiation in stem cells. Biomaterials Science 2017, 6: 189-199. PMID: 29189838, DOI: 10.1039/c7bm00733g.Peer-Reviewed Original ResearchConceptsStem cell osteogenic differentiationNanocomposite substrateCell osteogenic differentiationCell-imprinted substratesAtomic force microscopyWater contact angle measurementsOsteogenic differentiationNanoscale resolutionCultured stem cellsHydroxyapatite nanoparticlesContact angle measurementsDynamic mechanical thermal analysisForce microscopyStem cellsStem cell differentiationMechanical thermal analysisGene expression analysisElectron microscopyAngle measurementsChemical signalingExpression analysisOsteogenic differentiation capacityAlizarin red stainingChemical signalsCell differentiation
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