2014
Reinventing the Organism: Evolvability and Homology in Post-Dahlem Evolutionary Biology
Wagner G. Reinventing the Organism: Evolvability and Homology in Post-Dahlem Evolutionary Biology. Boston Studies In The Philosophy And History Of Science 2014, 307: 327-342. DOI: 10.1007/978-94-017-9412-1_15.Peer-Reviewed Original ResearchEvolutionary biologyDahlem ConferenceGenotype-phenotype mapStructure of organismsLimited pleiotropyNatural selectionEvolutionary causationPhenotype evolutionOrganism conceptRandom mutationsHomologyOrganismsEvolvabilityBiologyDevelopmental structuresMutationsDevelopmental organizationPleiotropySeedsFitnessSelectionAdaptation
2012
Coming to Grips with Evolvability
Pavlicev M, Wagner G. Coming to Grips with Evolvability. Evolution: Education And Outreach 2012, 5: 231-244. DOI: 10.1007/s12052-012-0430-1.Peer-Reviewed Original ResearchGenotype-phenotype mapOrganismal developmentMost genesCryptic mutationsPhenotypic traitsComplex organismsPhenotypic charactersMost traitsRandom mutationsReal organismsGenetic effectsEvolvabilityGenetic backgroundOrganismsGenesMutationsTraitsNew environmentRandom changesPhenotypeFitnessEvolutionSelectionConventional computer languages
2011
Robustness and evolvability in the B-system of flower development
Geuten K, Viaene T, Irish VF. Robustness and evolvability in the B-system of flower development. Annals Of Botany 2011, 107: 1545-1556. PMID: 21441246, PMCID: PMC3108807, DOI: 10.1093/aob/mcr061.Peer-Reviewed Original ResearchMeSH KeywordsComputer SimulationDNA Copy Number VariationsEvolution, MolecularFlowersGene DuplicationGene Expression Regulation, DevelopmentalGene Expression Regulation, PlantGene Regulatory NetworksGenes, HomeoboxGenes, PlantMADS Domain ProteinsModels, BiologicalPhenotypePhylogenyProtein Interaction MappingSolanaceaeConceptsStamen identityB geneB-function genesGene duplication eventsProtein-protein interactionsGene expression patternsDownstream gene regulationMore biological realismDuplication eventsDuplicate genesGene lineagesOrthologous genesGene duplicationFlower developmentGene familyGene regulationDownstream genesExpression patternsGenesNumber variationsRegulatory differencesEvolvabilityRegulatory systemBiological realismSolanaceae
2009
Predicting Virus Evolution: The Relationship between Genetic Robustness and Evolvability of Thermotolerance
Ogbunugafor CB, McBride RC, Turner PE. Predicting Virus Evolution: The Relationship between Genetic Robustness and Evolvability of Thermotolerance. Cold Spring Harbor Symposia On Quantitative Biology 2009, 74: 109-118. PMID: 19843592, DOI: 10.1101/sqb.2009.74.023.Peer-Reviewed Original ResearchConceptsGenetic robustnessVirus evolvabilityMutational inputExtant populationsEvolutionary biologistsEvolutionary eventsExperimental evolutionEvolutionary biologyVirus adaptabilityPhylogenetic methodsAdaptive thermotoleranceVirus evolutionEvolutionary processesHost populationsEvolvabilityPredictive scienceThermotoleranceNew environmentHistorical patternsMicrobesEvolutionBiologistsOrganismsBiologyCanalization
2008
Robustness promotes evolvability of thermotolerance in an RNA virus
McBride RC, Ogbunugafor CB, Turner PE. Robustness promotes evolvability of thermotolerance in an RNA virus. BMC Ecology And Evolution 2008, 8: 231. PMID: 18694497, PMCID: PMC2518931, DOI: 10.1186/1471-2148-8-231.Peer-Reviewed Original ResearchConceptsGenetic robustnessEfficacy of selectionNew habitatsEvolutionary biologyVirus adaptabilityLaboratory populationsMutational changesNew nichesEvolvabilityRNA virusesFace of perturbationsGreater toleranceThermotoleranceRobust clonesNovel environmentClonesBiological systemsBalance of robustnessFuture adaptationUnderlying mechanismHabitatsNicheBiologyGreater resistancePopulation
1999
Is Hsp90 a regulator of evolvability?
Wagner G, Chiu C, Hansen T. Is Hsp90 a regulator of evolvability? Journal Of Experimental Zoology 1999, 285: 116-118. PMID: 10440722, DOI: 10.1002/(sici)1097-010x(19990815)285:2<116::aid-jez3>3.0.co;2-p.Commentaries, Editorials and Letters
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