1989
Detection of Epstein–Barr Viral Genomes in Reed–Sternberg Cells of Hodgkin's Disease
Weiss LM, Movahed LA, Warnke RA, Sklar J. Detection of Epstein–Barr Viral Genomes in Reed–Sternberg Cells of Hodgkin's Disease. New England Journal Of Medicine 1989, 320: 502-506. PMID: 2536894, DOI: 10.1056/nejm198902233200806.Peer-Reviewed Original ResearchConceptsReed-Sternberg cellsEpstein-Barr virusHodgkin's diseaseSlot blot hybridizationEBV genomeBiopsy tissueTissue specimensEpstein-Barr viral genomeEBV nucleic acidsBlot hybridizationEBV DNASitu hybridizationSouthern blot hybridizationPositive specimensDiseasePatientsInfected cellsTissueIntense hybridizationSuch tissuesCellsViral genomePrevious studiesMonoclonality
1981
Copy number and location of Epstein-Barr viral genomes in neonatal human lymphocytes transformed after separation by size and treatment with mitogens
Anvret M, Miller G. Copy number and location of Epstein-Barr viral genomes in neonatal human lymphocytes transformed after separation by size and treatment with mitogens. Virology 1981, 111: 47-55. PMID: 6263010, DOI: 10.1016/0042-6822(81)90652-8.Peer-Reviewed Original ResearchConceptsNeonatal human lymphocytesEBV DNACell linesStaphylococcus aureusEpstein-Barr viral genomeHuman lymphocytesEBV DNA copiesEpstein-Barr virusPurified B lymphocytesFresh umbilical cordsB95-8 strainFicoll-Hypaque gradientDifferent cell linesEB virusMedian numberUmbilical cordB lymphocytesViral infectionViral genomeLymphocytesLipopolysaccharideSmall cell fractionPhysiologic stateTime of exposureCell fraction
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