Multi-omics approaches to decipher the interactions of nanoparticles and biological systems
Wang Y, Xiao Z, Wang Z, Lee D, Ma Y, Wilhelm S, Wang H, Kim B, Jiang W. Multi-omics approaches to decipher the interactions of nanoparticles and biological systems. Nature Reviews Bioengineering 2024, 3: 333-348. DOI: 10.1038/s44222-024-00264-4.Peer-Reviewed Original ResearchMulti-omics approachNano-bio interactionsMulti-OmicsMulti-omics pipelineMulti-omics dataSubcellular levelHigh-throughput mannerApplication of transcriptomicsNanoparticles in vivoMetabolomics technologyTreatment strategiesNanoparticle uptakeBiological systemsOptimized nanoparticlesEngineered nanoparticlesBiological informationImplementation of nanoparticlesClinical settingInteraction of nanoparticlesCell typesNano-bio interfaceEpigenomeTranscriptomeMetabolomicsBioinformaticsNanotechnology approaches to drug delivery for the treatment of ischemic stroke
Peng B, Mohammed F, Tang X, Liu J, Sheth K, Zhou J. Nanotechnology approaches to drug delivery for the treatment of ischemic stroke. Bioactive Materials 2024, 43: 145-161. PMID: 39386225, PMCID: PMC11462157, DOI: 10.1016/j.bioactmat.2024.09.016.Peer-Reviewed Original ResearchBlood-brain barrierClinical translationClinical trialsFDA-approved pharmacotherapiesReview therapeutic agentsIschemic strokeTherapeutic agentsEffective treatment optionDrug deliveryTreatment of ischemic strokePotential clinical translationGlobal public health concernImprove delivery efficiencyTreatment optionsTreatment strategiesIschemic brainPublic health concernStroke pharmacotherapyEngineered nanoparticlesStroke treatment strategiesDelivery efficiencyNanotechnological approachesDrugPharmacotherapyStroke
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