2025
Actin organizes chromosomes and microtubules to ensure mitotic fidelity in the preimplantation embryo
Hernandez B, Tetlak P, Domingo-Muelas A, Akizawa H, Skory R, Ardestani G, Biro M, Liu X, Bissiere S, Sakkas D, Plachta N. Actin organizes chromosomes and microtubules to ensure mitotic fidelity in the preimplantation embryo. Science 2025, 388: eads1234. PMID: 40403077, DOI: 10.1126/science.ads1234.Peer-Reviewed Original ResearchConceptsMitotic fidelityError-free chromosome segregationBranched actin filamentsPreimplantation embryosNuclear envelope breakdownRounds of cell divisionNuclear actinFilament disassemblyActin cablesActin filamentsChromosome segregationNuclear peripherySpindle elongationMammalian developmentCell divisionProphase chromosomesSpindle assembly mechanismsEnvelope breakdownAssembly mechanismsGenetic materialActinChromosomeMammalian embryosMouse embryosHuman embryos
2014
Nuclear Envelope Breakdown: Actin’ Quick to Tear Down the Wall
Mogessie B, Schuh M. Nuclear Envelope Breakdown: Actin’ Quick to Tear Down the Wall. Current Biology 2014, 24: r605-r607. PMID: 25004364, DOI: 10.1016/j.cub.2014.05.059.Peer-Reviewed Original Research
2008
Minor-class splicing occurs in the nucleus of the Xenopus oocyte
Friend K, Kolev NG, Shu MD, Steitz JA. Minor-class splicing occurs in the nucleus of the Xenopus oocyte. RNA 2008, 14: 1459-1462. PMID: 18567814, PMCID: PMC2491479, DOI: 10.1261/rna.1119708.Peer-Reviewed Original ResearchConceptsSmall nuclear ribonucleoproteinMinor class intronsU12-type splicingXenopus oocytesU12-dependent intronsNuclear envelope breakdownCertain eukaryotesMinor spliceosomeVertebrate cellsSplicing substrateNuclear compartmentNuclear ribonucleoproteinRNA intronsAccurate splicingEnvelope breakdownSplicingIntronsCytoplasmOocytesEukaryotesSpliceosomeMeiosisRibonucleoproteinNucleusSmall fraction
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