2004
Pindolol augmentation in depressed patients resistant to selective serotonin reuptake inhibitors: a double-blind, randomized, controlled trial.
Perry EB, Berman RM, Sanacora G, Anand A, Lynch-Colonese K, Charney DS. Pindolol augmentation in depressed patients resistant to selective serotonin reuptake inhibitors: a double-blind, randomized, controlled trial. The Journal Of Clinical Psychiatry 2004, 65: 238-43. PMID: 15003079, DOI: 10.4088/jcp.v65n0215.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAdultAgedConnecticutCross-Over StudiesDepressive Disorder, MajorDouble-Blind MethodDrug ResistanceDrug Therapy, CombinationFemaleFluoxetineHospitals, VeteransHumansMaleMiddle AgedParoxetinePersonality InventoryPindololSelective Serotonin Reuptake InhibitorsSertralineTreatment OutcomeVeteransConceptsSelective serotonin reuptake inhibitorsSerotonin reuptake inhibitorsPindolol augmentationMajor depressive disorderControl groupReuptake inhibitorsDepressed patientsDepressive disorderTreatment-resistant depressed patientsDSM-IV major depressive disorderEfficacy of pindololPartial response rateTreatment-resistant patientsPrimary outcome measureHAM-D scoresHamilton Rating ScaleSSRI monotherapyAdequate trialClinical responseAntidepressant responseSSRI administrationWeek 4Outcome measuresWeek 6Insufficient response
1999
The use of pindolol with fluoxetine in the treatment of major depression: final results from a double-blind, placebo-controlled trial
Berman R, Anand A, Cappiello A, Miller H, Hu X, Oren D, Charney D. The use of pindolol with fluoxetine in the treatment of major depression: final results from a double-blind, placebo-controlled trial. Biological Psychiatry 1999, 45: 1170-1177. PMID: 10331109, DOI: 10.1016/s0006-3223(98)00383-7.Peer-Reviewed Original ResearchConceptsPlacebo groupClinical responseMore weeksDrug-free outpatientsEfficacy of pindololPartial remission rateUse of pindololPlacebo-controlled trialDouble-blind mannerMajor depressive episodeSingle-blind mannerPindolol groupPindolol treatmentPartial remissionRemission rateBlood pressureReuptake inhibitorsStudy endPatient populationDepressive episodeDepressed patientsMajor depressionRecurrent depressionSide effectsControl group
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