2018
Hepatocellular Carcinoma Outcome is Predicted by Expression of Neuronal Calcium Sensor 1
Schuette D, Moore LM, Robert ME, Taddei TH, Ehrlich BE. Hepatocellular Carcinoma Outcome is Predicted by Expression of Neuronal Calcium Sensor 1. Cancer Epidemiology Biomarkers & Prevention 2018, 27: cebp.0167.2018. PMID: 29789326, PMCID: PMC8465775, DOI: 10.1158/1055-9965.epi-18-0167.Peer-Reviewed Original ResearchConceptsNeuronal calcium sensor-1Hepatocellular carcinomaDisease outcomePrognostic biomarkerIncidence of HCCWorse disease outcomesCancer-related deathLiver cancer cohortExpression levelsFurther functional assessmentEarly tumor detectionProspective cohortAsian patientsPatient survivalVariety of Ca2Tumor microarrayHCC patientsMetastatic cancerBreast cancerCancer cohortAggressive phenotypeNovel biomarkersFunctional assessmentPredictive valueTumor progression
2017
Early tumor detection afforded by in vivo imaging of near-infrared II fluorescence
Tao Z, Dang X, Huang X, Muzumdar MD, Xu ES, Bardhan NM, Song H, Qi R, Yu Y, Li T, Wei W, Wyckoff J, Birrer MJ, Belcher AM, Ghoroghchian PP. Early tumor detection afforded by in vivo imaging of near-infrared II fluorescence. Biomaterials 2017, 134: 202-215. PMID: 28482280, DOI: 10.1016/j.biomaterials.2017.04.046.Peer-Reviewed Original ResearchConceptsExogenous contrast agentsLanthanide nanoparticlesUnique nanoparticlesBiodegradable diblock copolymerRed fluorescent proteinOptical signalNIR-IINanoparticlesOVCAR-8 ovarian cancer cellsTumor accumulationTissue autofluorescenceOrganic fluorophoresContrast agentsTissue penetrationEarly tumor detectionFluorescent agentsOptical excitationEnhanced sensitivityIntrinsic reporterFluorescent proteinAccurate detectionNIRTumor detectionLuciferaseDiblock copolymers
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