1989
Association of transdermal nitroglycerin to vasopressin infusion in the treatment of variceal hemorrhage: A placebo‐controlled clinical trial
Bosch J, Groszmann R, García‐Pagán J, Terés J, García‐Tsao G, Navasa M, Mas A, Rodés J. Association of transdermal nitroglycerin to vasopressin infusion in the treatment of variceal hemorrhage: A placebo‐controlled clinical trial. Hepatology 1989, 10: 962-968. PMID: 2511136, DOI: 10.1002/hep.1840100612.Peer-Reviewed Original ResearchConceptsTransdermal nitroglycerinVariceal hemorrhageVariceal bleedingPlacebo-controlled clinical trialActive variceal bleedingEffectiveness of vasopressinDouble-blind techniqueSlow-release preparationHospital mortalityTransfusion requirementsRecurrent bleedingBalloon tamponadeCirrhotic patientsEmergency surgeryVasopressin infusionClinical trialsDefinitive controlDrug combinationsTotal doseNitroglycerinBleedingHemorrhagePatientsInitial controlVasopressin
1975
A Controlled Evaluation of Intravenous Adrenocorticotropic Hormone and Hydrocortisone in the Treatment of Acute Colitis
Kaplan H, Portnoy B, Binder H, Amatruda T, Spiko H. A Controlled Evaluation of Intravenous Adrenocorticotropic Hormone and Hydrocortisone in the Treatment of Acute Colitis. Gastroenterology 1975, 69: 91-95. PMID: 168121, DOI: 10.1016/s0016-5085(19)32640-x.Peer-Reviewed Original ResearchConceptsIntravenous adrenocorticotropic hormoneAdrenocorticotropic hormoneSymptomatic inflammatory bowel diseaseSystemic steroid levelsInflammatory bowel diseaseDouble-blind techniqueTreatment of patientsConsecutive hospital patientsPlasma cortisol levelsIntravenous hydrocortisoneTherapeutic lagAcute colitisBowel diseasePatient evaluationHospital patientsDrug dosesControlled EvaluationEquivalent dosageSteroid levelsCortisol levelsExcretion rateDrug selectionHydrocortisonePatientsBlind technique
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