2013
Reconstructing dynamic microRNA-regulated interaction networks
Schulz MH, Pandit KV, Cardenas C, Ambalavanan N, Kaminski N, Bar-Joseph Z. Reconstructing dynamic microRNA-regulated interaction networks. Proceedings Of The National Academy Of Sciences Of The United States Of America 2013, 110: 15686-15691. PMID: 23986498, PMCID: PMC3785769, DOI: 10.1073/pnas.1303236110.Peer-Reviewed Original ResearchConceptsTranscription factorsGene expressionDynamic Regulatory Events MinerTemporal gene expressionDynamic regulatory networksSpecific developmental phasesMRNA expression dataLung developmentRegulatory networksMiRNA targetsInteraction networksImportant miRNAsExpression dataMiRNAsAdditional miRNAsLung differentiationDevelopmental phasesMiRNAPostnatal lung developmentProgression pathwaysProliferation assaysExpressionRegulationMRNA expressionMicroRNAs
2006
Phase-specific gene expression underlying morphological adaptations of the dimorphic human pathogenic fungus, Coccidioides posadasii
Johannesson H, Kasuga T, Schaller RA, Good B, Gardner MJ, Townsend JP, Cole GT, Taylor JW. Phase-specific gene expression underlying morphological adaptations of the dimorphic human pathogenic fungus, Coccidioides posadasii. Fungal Genetics And Biology 2006, 43: 545-559. PMID: 16697669, DOI: 10.1016/j.fgb.2006.02.003.Peer-Reviewed Original ResearchConceptsGene expressionPhase-specific gene expressionPathogenic phaseNumber of genesConsistent differential expressionOpen reading frameDimorphic fungal pathogenDimorphic human pathogenic fungusHuman pathogenic fungiTranscriptional profilingEntire speciesEnvironmental stressReading frameComparative hybridizationMorphological adaptationsFungal pathogensCandidate genesSaprobic phasePathogenic fungiMetabolism of lipidsDifferential expressionGenesFungal isolatesElevated expressionDevelopmental phases
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