2025
Interpersonal problems as a predictor of treatment outcome in adult depression: An individual participant data meta-analysis
Gómez Penedo J, Meglio M, Flückiger C, Wienicke F, Breunese J, Menchetti M, Rucci P, Johansson R, Town J, Abbass A, Lilliengren P, Bagby R, Quilty L, Lemmens L, van Bronswijk S, Barkham M, Stiles W, Hardy G, Fonagy P, Luyten P, Constantinou M, Barber J, McCarthy K, Solomonov N, Joyce A, Cuijpers P, Driessen E. Interpersonal problems as a predictor of treatment outcome in adult depression: An individual participant data meta-analysis. Clinical Psychology Review 2025, 118: 102570. PMID: 40158500, DOI: 10.1016/j.cpr.2025.102570.Peer-Reviewed Original ResearchConceptsInterpersonal problemsInterpersonal distressAdult depressionParticipant data meta-analysisTreatment outcomesPredictors of treatment outcomeDepression treatment outcomesData Meta-AnalysisDepressive symptom levelsIPD-MAMeta-analytic strategiesEffect of treatment typePost-treatmentTherapist effectsCommunion dimensionIndividual Participant Data Meta-AnalysisSymptom levelsStudy-level meta-analysesPrimary study analysisMeta-analysisTreatment typeDepressionFollow-upEffect sizeModerating effect
2023
Personalized symptom clusters that predict depression treatment outcomes: A replication of machine learning methods
Chen Y, Stewart J, Ge J, Cheng B, Chekroud A, Hellerstein D. Personalized symptom clusters that predict depression treatment outcomes: A replication of machine learning methods. Journal Of Affective Disorders Reports 2023, 11: 100470. DOI: 10.1016/j.jadr.2023.100470.Peer-Reviewed Original ResearchHamilton Rating ScaleSymptom clustersTreatment trajectoriesQuick InventoryTreatment outcomesDouble-blind clinical trialDepressive Symptomatology-Self ReportRating ScaleBest baseline predictorsHAM-D scoresDepression treatment outcomesAnxiety disorder diagnosisQIDS-SR16Depressive illnessEscitalopram monotherapyBaseline variablesClinical trialsBaseline predictorsTreatment efficacyUnipolar depressionDifferent treatment trajectoriesTreatment planLogistic regressionDisorder diagnosisDual treatment
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