Targeting APRIL in the treatment of glomerular diseases
Cheung C, Barratt J, Lafayette R, Liew A, Suzuki Y, Tesař V, Trimarchi H, Wong M, Zhang H, Rizk D. Targeting APRIL in the treatment of glomerular diseases. Kidney International 2024, 106: 806-818. PMID: 39182759, DOI: 10.1016/j.kint.2024.08.012.Peer-Reviewed Original ResearchGlomerular diseaseB cell depletion strategiesCytokine B cell-activating factorDeleterious host immune responsesFunctionality of humoral immunityMemory B-cell functionB-cell activating factorProliferation inducing ligandTreatment of glomerular diseasesB cell functionB cell developmentB cell survivalImmunoglobulin class switchingResponse to vaccinationClinical trial dataHost immune responseTumour necrosis factor (TNF)-superfamilyImmunomodulatory approachesAutoimmune diseasesClinical developmentInducing ligandIgA nephropathyHumoral immunityTherapeutic inhibitionClass switching
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply