Secretory Lysosome Biogenesis in Cytotoxic T Lymphocytes from Normal and Chediak Higashi Syndrome Patients
Stinchcombe J, Page L, Griffiths G. Secretory Lysosome Biogenesis in Cytotoxic T Lymphocytes from Normal and Chediak Higashi Syndrome Patients. Traffic 2000, 1: 435-444. PMID: 11208129, DOI: 10.1034/j.1600-0854.2000.010508.x.Peer-Reviewed Original ResearchConceptsSecretory lysosomesLysosomal biogenesisMutant cellsChediak-Higashi syndromeCytotoxic T lymphocytesWild-typeEndocytic pathwayT lymphocytesChediak-Higashi syndrome patientsLytic proteinsBiogenesisDelivery of proteinsLysosome formationGenetic diseasesResting cellsTarget cellsLysosomesCytotoxic T lymphocyte clonesCell aggregatesTarget cell killingCell maturationResting T lymphocytesProteinCellsCell killing
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