Phase II Study of Low Dose and High Dose Conjugated Estrogen for Androgen Independent Prostate Cancer
Pomerantz M, Manola J, Taplin M, Bubley G, Inman M, Lowell J, Beard C, Kantoff P, Oh W. Phase II Study of Low Dose and High Dose Conjugated Estrogen for Androgen Independent Prostate Cancer. Journal Of Urology 2007, 177: 2146-2150. PMID: 17509304, DOI: 10.1016/j.juro.2007.01.119.Peer-Reviewed Original ResearchConceptsAndrogen-independent prostate cancerIndependent prostate cancerProstate specific antigenProstate cancerSpecific antigenDose armProgressive androgen-independent prostate cancerAdministered to most patientsStudy of low doseAndrogen-independent diseaseHigh dose armLow dose armProphylactic breast irradiationPhase II studyMonths of treatmentDehydroepiandrosterone sulfate levelsRisk of thromboembolismWarfarin 1 mgBreast irradiationThromboembolic eventsThromboembolic complicationsTherapeutic optionsConjugated estrogensMost patientsPremarin
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