A robust blood gene expression-based prognostic model for castration-resistant prostate cancer
Wang L, Gong Y, Chippada-Venkata U, Heck M, Retz M, Nawroth R, Galsky M, Tsao C, Schadt E, de Bono J, Olmos D, Zhu J, Oh W. A robust blood gene expression-based prognostic model for castration-resistant prostate cancer. BMC Medicine 2015, 13: 201. PMID: 26297150, PMCID: PMC4546313, DOI: 10.1186/s12916-015-0442-0.Peer-Reviewed Original ResearchConceptsFour-gene modelCRPC patientsProstate cancerClinical parametersBackgroundCastration-resistant prostate cancerCastration-resistant prostate cancerSurvival of CRPC patientsGene-expression-based prognostic modelsBiomarker modelProstate cancer lethalityImmune cell componentsGene modelsGenes associated with cancer progressionMRNA profilesIntegrative genomic analysisWorse survivalPrognostic improvementBiological processesClinical predictorsAssociated with wide variationsCancer lethalityMyeloid cellsIntegrative genomics approachPrognostic powerCRPC
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