Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine
Deshmukh A, Peijs L, Beaudry J, Jespersen N, Nielsen C, Ma T, Brunner A, Larsen T, Bayarri-Olmos R, Prabhakar B, Helgstrand C, Severinsen M, Holst B, Kjaer A, Tang-Christensen M, Sanfridson A, Garred P, Privé G, Pedersen B, Gerhart-Hines Z, Nielsen S, Drucker D, Mann M, Scheele C. Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine. Cell Metabolism 2019, 30: 963-975.e7. PMID: 31668873, DOI: 10.1016/j.cmet.2019.10.001.Peer-Reviewed Original ResearchConceptsHuman adipocytesExtracellular matrix proteinsWhite adipocytesComparative mappingAdipose secretomeMatrix proteinsMetabolic crosstalkImportant regulatorFunctional studiesProtein 1ProteinBrown adipocytesSecretomeWhite adipose tissueWhite adipose depotsProteomicsAdipocytesBrown adiposeGrowth factorHuman brownCell mediumBatokinesAdipose depotsAdipose tissueComplement system
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