2017
p53 binding sites in normal and cancer cells are characterized by distinct chromatin context
Bao F, LoVerso PR, Fisk JN, Zhurkin VB, Cui F. p53 binding sites in normal and cancer cells are characterized by distinct chromatin context. Cell Cycle 2017, 16: 2073-2085. PMID: 28820292, PMCID: PMC5731425, DOI: 10.1080/15384101.2017.1361064.Peer-Reviewed Original ResearchConceptsP53 binding siteHistone marksTranscription factorsDNA-binding transcription factorsP53 sitesCancer cellsRepressive histone marksContext of chromatinActive histone marksDistinct epigenetic featuresPioneer transcription factorsHigh nucleosome occupancyP53-DNA interactionsEndogenous retroviral elementsBinding sitesSequence-dependent mannerChromatin environmentChromatin contextNucleosome occupancyTranscriptional networksRepeat familyCognate sitesDNA methylationEpigenetic featuresP53 interacts
1995
Minute virus of mice transcriptional activator protein NS1 binds directly to the transactivation region of the viral P38 promoter in a strictly ATP-dependent manner
Christensen J, Cotmore S, Tattersall P. Minute virus of mice transcriptional activator protein NS1 binds directly to the transactivation region of the viral P38 promoter in a strictly ATP-dependent manner. Journal Of Virology 1995, 69: 5422-5430. PMID: 7636987, PMCID: PMC189388, DOI: 10.1128/jvi.69.9.5422-5430.1995.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphateAnimalsBase SequenceBinding SitesCell LineDeoxyribonuclease IDNA, ViralGenes, ViralGenetic VectorsGenome, ViralMinute virus of miceMolecular Sequence DataNucleopolyhedrovirusesPlasmidsPromoter Regions, GeneticRecombinant ProteinsSpodopteraTranscriptional ActivationTransfectionViral Nonstructural ProteinsViral ProteinsConceptsATP-dependent mannerGamma S-ATPTransactivation regionP38 promoterCognate sitesDNA fragmentsNS1 bindsCore DNA sequenceCarboxy-terminal peptidePotent transcriptional activatorMinute virusS-ATPTranscriptional activatorMVM genomeATP bindingTAR sequenceTATA boxDNA sequencesATP hydrolysisBiochemical stepsBp 5DNase INS1 polypeptideTAR bindingAntibodies
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