Phase II trial of gemcitabine plus cisplatin in patients with metastatic urothelial cancer.
Kaufman D, Raghavan D, Carducci M, Levine E, Murphy B, Aisner J, Kuzel T, Nicol S, Oh W, Stadler W. Phase II trial of gemcitabine plus cisplatin in patients with metastatic urothelial cancer. Journal Of Clinical Oncology 2000, 18: 1921-7. PMID: 10784633, DOI: 10.1200/jco.2000.18.9.1921.Peer-Reviewed Original ResearchConceptsMetastatic urothelial cancerTreatment of metastatic urothelial cancerChemotherapy-naive patientsUrothelial cancerMedian time to treatment failurePhase II trial of gemcitabineTreatment of chemotherapy-naive patientsDay 1Time to treatment failureStage IV carcinomaTrial of gemcitabineCombination of gemcitabinePhase II trialClinical safety profileHematologic toxicityCisplatin doseIV carcinomaPartial responseMedian survivalTreatment failureSafety profileSevere toxicityGemcitabineChemotherapeutic agentsDisease progression
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