2006
MHC Class II Expression Identifies Functionally Distinct Human Regulatory T Cells
Baecher-Allan C, Wolf E, Hafler DA. MHC Class II Expression Identifies Functionally Distinct Human Regulatory T Cells. The Journal Of Immunology 2006, 176: 4622-4631. PMID: 16585553, DOI: 10.4049/jimmunol.176.8.4622.Peer-Reviewed Original ResearchConceptsContact-dependent suppressionRegulatory T cellsT cellsCD4 cellsDR expressionFunctional MHC class II moleculesRegulatory T cell populationHuman regulatory T cellsMHC class II determinantsIL-10 secretionClass II determinantsMHC class II moleculesHigh Foxp3 expressionMHC-II expressionEarly IL-4T cell populationsT cell nonresponsivenessClass II moleculesEx vivo expressionVivo expressionHuman CD4 cellsSubpopulations CD4Treg populationFoxp3 expressionIL-4
1991
Signal requirements for the generation of CD4+ and CD8+ T-cell responses to human allogeneic microvascular endothelium.
Pardi R, Bender J. Signal requirements for the generation of CD4+ and CD8+ T-cell responses to human allogeneic microvascular endothelium. Circulation Research 1991, 69: 1269-1279. PMID: 1934357, DOI: 10.1161/01.res.69.5.1269.Peer-Reviewed Original ResearchConceptsT cell precursorsEndothelial cellsInterleukin-2T cellsT lymphocytesMicrovascular endotheliumT cell-mediated immune responsesMajor T cell subsetsSpecific cytotoxic T lymphocytesMonocyte/macrophage seriesMHC class II determinantsCD3/T cell receptor complexIndividual cell subsetsGeneration of CD4Effector T cellsClass II determinantsT cell responsesT cell subsetsAdoptive transfer experimentsAllogeneic endothelial cellsClass I determinantsSelf-MHC moleculesCytotoxic T lymphocytesMonocytes/macrophagesT cell receptor complexInduction of specific T-cell responsiveness to allogeneic bone.
Horowitz M, Friedlaender G. Induction of specific T-cell responsiveness to allogeneic bone. Journal Of Bone And Joint Surgery 1991, 73: 1157-68. PMID: 1716256, DOI: 10.2106/00004623-199173080-00004.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, Differentiation, T-LymphocyteBone and BonesBone MarrowBone TransplantationCells, CulturedCytotoxicity Tests, ImmunologicEpitopesLymphocyte ActivationLymphocyte Culture Test, MixedMajor Histocompatibility ComplexMiceMice, Inbred StrainsT-LymphocytesTransplantation, HomologousTransplantation, IsogeneicConceptsT cellsAllogeneic boneMajor histocompatibility complexHistocompatibility complexAlloreactive T cellsClass II determinantsPurified T cellsSpecific immune responseT cell responsivenessMixed lymphocyte cultureCell surface phenotypeStrains of miceBone marrow cellsState of activationStimulating antigenImmune responseBone donorsAntigen specificityBone marrowLymphocyte culturesSecondary exposurePrimed cellsResponding cellsAntigenBone
1986
Physiologic Regulation of Class II Major Histocompatibility Complex Gene Expression
Collins T, Pober J, Strominger J. Physiologic Regulation of Class II Major Histocompatibility Complex Gene Expression. 1986, 14-31. DOI: 10.1007/978-3-642-70367-6_2.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsClass II determinantsNominal antigenMajor histocompatibility complexSpecific effector cellsClass II major histocompatibility complexT helper cellsAntigen-presenting cellsClass II antigensCase of transplantationMajor histocompatibility complex gene expressionT-inducer cellsClass II major histocompatibility complex gene expressionT cell antigen receptorAccessory capacityEffector cellsAllogeneic responseHelper cellsInducer cellsII antigensImmune responsivenessImmune systemCell antigen receptorAntigenAntigen receptorHistocompatibility complex
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply