2023
Prophylactic Efficacy of Riluzole against Anxiety- and Depressive-Like Behaviors in Two Rodent Stress Models
Bansal Y, Fee C, Misquitta K, Codeluppi S, Sibille E, Berman R, Coric V, Sanacora G, Banasr M. Prophylactic Efficacy of Riluzole against Anxiety- and Depressive-Like Behaviors in Two Rodent Stress Models. Complex Psychiatry 2023, 9: 57-69. PMID: 37101541, PMCID: PMC10123365, DOI: 10.1159/000529534.Peer-Reviewed Original ResearchUnpredictable chronic mild stressAnhedonia-like behaviorHelplessness-like behaviorStress-related disordersFirst-line antidepressant drugsNovelty-induced hypophagia testDepressive-like behaviorChronic mild stressHigh relapse rateSucrose consumption testNovelty-suppressed feedingRodent stress modelsMajor depressive disorderAnxiety-like behaviorOpen field testBehavioral emotionalityRiluzole efficacyRiluzole treatmentHypophagia testRelapse rateProphylactic medicationStress-related illnessesProphylactic efficacyProphylactic treatmentSpecific symptom dimensions
2022
Utility and Implementation of Oral Corticosteroid Exposure in Behavioral Neuroscience Research with Rodents
Sequeira M, Taylor J, Gourley S. Utility and Implementation of Oral Corticosteroid Exposure in Behavioral Neuroscience Research with Rodents. Neuromethods 2022, 190: 223-231. DOI: 10.1007/978-1-0716-2748-8_12.Peer-Reviewed Original ResearchChronic antidepressant treatmentChronic CORT exposureDepression-like phenomenaHelplessness-like behaviorOral corticosteroid exposureDepressive-like stateNeurobiology of depressionChronic mild stressCohort of animalsMultiple biological factorsCorticosteroid exposureAntidepressant actionAntidepressant treatmentAdrenal hormonesC57BL/6 miceCORT exposureResilient miceNaïve rodentsMild stressExposure resultsMiceExposure procedureCorticosteroneExposure periodDepression
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