2000
Nicotine inhibits firing activity of dorsal raphe 5-HT neurones in vivo
Engberg G, Erhardt S, Sharp T, Hajós M. Nicotine inhibits firing activity of dorsal raphe 5-HT neurones in vivo. Naunyn-Schmiedeberg's Archives Of Pharmacology 2000, 362: 41-45. PMID: 10935531, DOI: 10.1007/s002100000252.Peer-Reviewed Original ResearchConceptsEffects of nicotineDorsal rapheChloral hydrate-anaesthetised ratsNicotine antagonist mecamylamineBrain monoaminergic systemsDependence-inducing drugsExtracellular electrophysiological recordingsMicroiontophoretic applicationAntagonist mecamylamineAfferent pathwaysMonoaminergic systemsReceptor antagonistNicotine inhibitsApparent tachyphylaxisElectrophysiological recordingsFiring rateNeuronesNicotineInhibitory effectRapheTransient inhibitionPossible involvementInhibitionTachyphylaxisChlorisondamine
1988
Role of primary sensory neurons in the central effects of nicotine
Hajós M, Engberg G. Role of primary sensory neurons in the central effects of nicotine. Psychopharmacology 1988, 94: 468-470. PMID: 2897701, DOI: 10.1007/bf00212839.Peer-Reviewed Original ResearchConceptsC-fiber afferentsLocus coeruleusCentral NA neuronsGanglionic blocker hexamethoniumPrimary sensory neuronsAction of nicotineEffects of nicotineLC firing rateSingle-unit recordingsLC dischargeNeonatal treatmentLC neuronsNA neuronsCentral effectsSelective degenerationSensory neuronsUnit recordingsLow dosesFiring rateNicotineNeuronsAfferentsChlorisondamineHexamethoniumNoradrenaline
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply