Recent Progress in Deciphering the Etiopathogenesis of Primary Membranous Nephropathy
Kronbichler A, Oh J, Meijers B, Mayer G, Shin J. Recent Progress in Deciphering the Etiopathogenesis of Primary Membranous Nephropathy. BioMed Research International 2017, 2017: 1936372. PMID: 28904948, PMCID: PMC5585565, DOI: 10.1155/2017/1936372.Peer-Reviewed Original ResearchConceptsPrimary membranous nephropathyMembranous nephropathyThrombospondin type-1 domain-containing 7AM-type phospholipase A2 receptorFrequency of spontaneous remissionReduction of proteinuriaImpaired renal functionPhospholipase A2 receptorRecurrence of diseaseDecline of kidney functionChildhood MNPLA2R1 geneImmunological remissionPLA2R antibodyHigher proteinuriaPrimary MNRenal functionRenal transplantationSpontaneous remissionTreatment resistanceA2 receptorsEpitope spreadingNephrotic syndromeTreatment responseCationic bovine serum albumin
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