DeepVelo: Single-cell transcriptomic deep velocity field learning with neural ordinary differential equations
Chen Z, King W, Hwang A, Gerstein M, Zhang J. DeepVelo: Single-cell transcriptomic deep velocity field learning with neural ordinary differential equations. Science Advances 2022, 8: eabq3745. PMID: 36449617, PMCID: PMC9710871, DOI: 10.1126/sciadv.abq3745.Peer-Reviewed Original ResearchOrdinary differential equationsDifferential equationsTranscriptome dynamicsSingle-cell gene expression measurementsNeural ordinary differential equationsSingle-cell sequencing technologiesVelocity fieldIndividual cellsGene expression changesGene expression profilesDynamical systemsGene expression measurementsTranscriptional dynamicsRNA velocityDifferent sequencing platformsChaotic propertiesSequencing technologiesCell statesPerturbation analysisRegulatory relationshipsData-Driven DiscoveryExpression changesExpression profilesSequencing platformsDriver genes
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