2023
Exploiting a rodent cell block for intrinsic resistance to HIV-1 gene expression in human T cells
Behrens R, Rajashekar J, Bruce J, Evans E, Hansen A, Salazar-Quiroz N, Simons L, Ahlquist P, Hultquist J, Kumar P, Sherer N. Exploiting a rodent cell block for intrinsic resistance to HIV-1 gene expression in human T cells. MBio 2023, 14: e00420-23. PMID: 37676006, PMCID: PMC10653828, DOI: 10.1128/mbio.00420-23.Peer-Reviewed Original ResearchConceptsCyclin T1Species-specific differencesViral gene expressionGene expressionHost proteinsIntron-containing viral RNAsBroad-spectrum resistanceHost cell biologyCRISPR/Cas9 geneLatency reversal agentsIsogenic cell linesHuman T cellsEfficient HIV-1 transcriptionHIV-1 gene expressionCell linesViral RNA transcriptionT cellsSpecies-specific regionsCell-intrinsic defectHIV-1 virion productionHousekeeping proteinsNuclear exportRNA transcriptionCell biologyCas9 gene
2011
A repertoire independent and cell intrinsic defect in murine GVHD induction by effector memory T cells (169.6)
Juchem K, Anderson B, Zhang C, McNiff J, Demetris A, Caton A, Shlomchik W, Shlomchik M. A repertoire independent and cell intrinsic defect in murine GVHD induction by effector memory T cells (169.6). The Journal Of Immunology 2011, 186: 169.6-169.6. DOI: 10.4049/jimmunol.186.supp.169.6.Peer-Reviewed Original ResearchMemory T cellsEffector memory T cellsT cellsGVHD inductionAllogeneic stem cell transplantationMemory T cell poolCentral memory T cellsT cell receptor transgenicT cell receptor repertoireT cell poolStem cell transplantationCell receptor repertoireNaïve T cellsTg T cellsSyngeneic bone marrowCell-intrinsic defectTransient GVHDHost diseasePost transplantMajor complicationsPD-1PD-L1Transgenic recipientsCell transplantationNaive CD4
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply