OVERTURE Phase 2 MRI Analysis Demonstrates Reduced Corpus Callosum Atrophy in Alzheimer's Disease
Da X, Hempel E, Hajos M, Kern R, Cimenser A. OVERTURE Phase 2 MRI Analysis Demonstrates Reduced Corpus Callosum Atrophy in Alzheimer's Disease. Alzheimer's & Dementia 2024, 20: e085446. PMCID: PMC11714734, DOI: 10.1002/alz.085446.Peer-Reviewed Original ResearchMagnetic resonance imagingMonth 3Midsagittal planeDiffusion tensor imagingPhase 3 clinical trialsRegional structural alterationsCorpus callosumT1w MRI imagesMonths of treatmentCommissural white matter tractsCorpus callosum atrophyWhite matter atrophyAlzheimer's diseaseSensory stimulationMonth 6CC atrophyClinical trialsSham groupWhite matter tractsGamma frequenciesVisual stimulationResonance imaging
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