2023
Cancer Relevance of Circulating Antibodies Against LINE-1 Antigens in Humans
Vylegzhanina A, Bespalov I, Novototskaya-Vlasova K, Hall B, Gleiberman A, Yu H, Leontieva O, Leonova K, Kurnasov O, Osterman A, Dy G, Komissarov A, Vasilieva E, Gehlhausen J, Iwasaki A, Ambrosone C, Tsuji T, Matsuzaki J, Odunsi K, Andrianova E, Gudkov A. Cancer Relevance of Circulating Antibodies Against LINE-1 Antigens in Humans. Cancer Research Communications 2023, 3: 2256-2267. PMID: 37870410, PMCID: PMC10631453, DOI: 10.1158/2767-9764.crc-23-0289.Peer-Reviewed Original ResearchConceptsL1 antigenCancer typesDisease stage 1Discovery of autoantibodiesHigh IgG titersTumor-associated antigensDetermination of immunoreactivityTumor immunoreactivityCirculating AntibodiesIgG titersAntibody responseImmune responseLiver cancerReactive IgGHealthy individualsCurable cancer typesImmune systemAntigenNormal tissuesPatientsCancerEarly detectionElevated levelsCarcinogenic processAutoantibodies
2022
Patient-Derived Xenotransplant of CNS Neoplasms in Zebrafish: A Systematic Review
Sarmiento B, Callegari S, Ghotme K, Akle V. Patient-Derived Xenotransplant of CNS Neoplasms in Zebrafish: A Systematic Review. Cells 2022, 11: 1204. PMID: 35406768, PMCID: PMC8998145, DOI: 10.3390/cells11071204.Peer-Reviewed Original ResearchConceptsAssociated with poor survivalCentral nervous system tumorsNervous system tumorsCentral nervous system malignant tumorNeuro-oncology fieldPrimary cell culturesSystem malignant tumorResults of xenotransplantationCNS tumorsTumor microenvironmentSystem tumorsCNS neoplasmsMalignant tumorsTumor progressionPediatric populationPoor survivalTumorImprove outcomesCarcinogenic processMolecular genotypingSystematic reviewNeuroblastomaEffects of different treatmentsGlioblastomaZebrafish model
2010
DNA Aptamers as Molecular Probes for Colorectal Cancer Study
Sefah K, Meng L, Lopez-Colon D, Jimenez E, Liu C, Tan W. DNA Aptamers as Molecular Probes for Colorectal Cancer Study. PLOS ONE 2010, 5: e14269. PMID: 21170319, PMCID: PMC3000811, DOI: 10.1371/journal.pone.0014269.Peer-Reviewed Original ResearchConceptsColorectal cancerAppropriate therapeutic regimensCell-based systematic evolutionColorectal cancer studyMolecular featuresMultistep carcinogenic processCancer cell linesCell line DLD-1Therapeutic regimensNormal colon cellsPrognostic markerDifferent tumorsSpecific tumorsFlow cytometrySpecific biomarkersEarly disease detectionCarcinogenic processTumorsCancerSpecific markersCancer studiesColon cellsDLD-1Cell linesDisease development
2003
Priorities for development of research methods in occupational cancer.
Ward EM, Schulte PA, Bayard S, Blair A, Brandt-Rauf P, Butler MA, Dankovic D, Hubbs AF, Jones C, Karstadt M, Kedderis GL, Melnick R, Redlich CA, Rothman N, Savage RE, Sprinker M, Toraason M, Weston A, Olshan AF, Stewart P, Zahm SH, Team O. Priorities for development of research methods in occupational cancer. Environmental Health Perspectives 2003, 111: 1-12. PMID: 12524210, PMCID: PMC1241299, DOI: 10.1289/ehp.111-1241299.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsNational Occupational Research AgendaOccupational cancerOccupational cancer researchNumber of cancersCancer researchSecondary preventionSignificant morbidityOccupational cohortOccupational carcinogensEpidemiologic studiesOccupational factorsCarcinogenic processHealth effectsCancerEnvironmental toxicantsIndustrial HygienistsPriority research areasMorbidityRisk assessmentCohortMortalityTeam of expertsHygienistsPrevention
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