2022
Foreign body response to synthetic polymer biomaterials and the role of adaptive immunity
Kyriakides TR, Kim HJ, Zheng C, Harkins L, Tao W, Deschenes E. Foreign body response to synthetic polymer biomaterials and the role of adaptive immunity. Biomedical Materials 2022, 17: 022007. PMID: 35168213, PMCID: PMC9159526, DOI: 10.1088/1748-605x/ac5574.Peer-Reviewed Original ResearchConceptsAdaptive immune cellsForeign body reactionImmune cellsAdaptive immunityImmune-inflammatory cellsSpecific macrophage subsetsSpecific antibody responseForeign body giant cellsWound repair cellsInflammatory cellsAntibody responseFavorable outcomeMacrophage subtypesDistinct immuneMacrophage subsetsB cellsGiant cellsRegenerative responseBody reactionRepair cellsImmunityForeign body responseExact participationBody responseContradictory studiesContact Dermatitis and Topical Agents
Milam E, Price A, Ramachandran S, Cohen D. Contact Dermatitis and Topical Agents. 2022, 57-71. DOI: 10.1002/9781119676881.ch6.Peer-Reviewed Original ResearchContact dermatitisSkin reactionsAdverse skin reactionsIrritant contact dermatitisAllergic contact dermatitisSun-damaged skinForeign body reactionInvasive cosmetic proceduresTopical agentsContact urticariaThorough historyCommon causePreservative allergyDermatitisDermatologic practiceClinical settingContact dermatosesOphthalmic preparationsAllergyPhototoxic dermatitisCosmetic proceduresIrritant propertiesBody reactionEnvironmental exposuresCosmetic treatment
2015
A Nodular Foreign Body Reaction in a Dialysis Patient Receiving Long-term Treatment With Lanthanum Carbonate
Valika AK, Jain D, Jaffe PE, Moeckel G, Brewster UC. A Nodular Foreign Body Reaction in a Dialysis Patient Receiving Long-term Treatment With Lanthanum Carbonate. American Journal Of Kidney Diseases 2015, 67: 128-132. PMID: 26385816, DOI: 10.1053/j.ajkd.2015.07.033.Peer-Reviewed Case Reports and Technical NotesConceptsEnd-stage renal diseaseLanthanum carbonate treatmentUpper gastrointestinal bleedSimilar pathologic findingsLong-term treatmentCollections of histiocytesForeign body reactionGastrointestinal bleedGastrointestinal bleedingUpper endoscopyDialysis patientsHIV infectionRenal diseaseComorbid conditionsPathologic findingsAdverse reactionsHyperechoic materialEndoscopic ultrasoundHyperplastic epitheliumPhosphate bindersGiant cellsLanthanum carbonateGranular cytoplasmic materialPatientsBody reaction
2004
The CC Chemokine Ligand, CCL2/MCP1, Participates in Macrophage Fusion and Foreign Body Giant Cell Formation
Kyriakides TR, Foster MJ, Keeney GE, Tsai A, Giachelli CM, Clark-Lewis I, Rollins BJ, Bornstein P. The CC Chemokine Ligand, CCL2/MCP1, Participates in Macrophage Fusion and Foreign Body Giant Cell Formation. American Journal Of Pathology 2004, 165: 2157-2166. PMID: 15579457, PMCID: PMC1618731, DOI: 10.1016/s0002-9440(10)63265-8.Peer-Reviewed Original ResearchConceptsForeign body giant cellsForeign body reactionCC chemokine ligand 2CCL2-null miceChemokine ligand 2CC chemokine ligandBlood-borne monocytesPeripheral blood monocytesWild-type miceCCL2/MCP1Chemokine ligandGiant cell formationMonocyte recruitmentBlood monocytesFBGC formationMacrophage fusionGiant cellsImplantation sitesBody reactionForeign body giant cell formationMiceInhibitory peptidesCCL2 functionMonocytesChemotactic signals
1998
Pathologic supracondylar fracture due to osteolytic pseudotumor of knee following cementless total knee replacement
Benevenia J, Lee F, Buechel F, Parsons J. Pathologic supracondylar fracture due to osteolytic pseudotumor of knee following cementless total knee replacement. Journal Of Biomedical Materials Research 1998, 43: 473-477. PMID: 9855207, DOI: 10.1002/(sici)1097-4636(199824)43:4<473::aid-jbm16>3.0.co;2-9.Peer-Reviewed Original ResearchConceptsWear debrisForeign body reactionPathologic fractureSupracondylar fracturesReplacement arthroplastyDebris of polyethyleneTotal knee replacement arthroplastyCementless total knee replacementAggressive granulomatous lesionsBody reactionKnee replacement arthroplastyJoint replacement arthroplastySoft tissue massTotal knee replacementAseptic prosthetic looseningTotal knee prosthesisMassive osteolysisGranulomatous lesionsTumorlike lesionsKnee replacementProsthetic looseningTissue massFemoral componentLesionsKnee prosthesis
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