Treatment of Melasma Using Low-Fluence QS Nd: YAG (1064 nm) Laser: A Blind, Randomized, Placebo-Controlled Trial.
Sadeghpour M, Laughter M, Rizzo S, Depina J, Petrell K, Arndt K, Dover J. Treatment of Melasma Using Low-Fluence QS Nd: YAG (1064 nm) Laser: A Blind, Randomized, Placebo-Controlled Trial. Dermatologic Surgery 2025 PMID: 40932145, DOI: 10.1097/dss.0000000000004846.Peer-Reviewed Original ResearchTreatment of melasmaHydroquinone 4%Patient-reported improvementQS-NdMelanin indexFitzpatrick skin types I-IVSkin types I-IVQS Nd:YAG laserPlacebo-controlled trialLaser treatment groupMelasma severity scoreSplit face trialStatistically significant differenceMMASI scoreTopical therapyPlacebo-ControlledTypes I-IVMonths treatmentFollow-upInadequately controlled studiesWeek 8Severity scoreTreatment protocolsMelasmaTreatment groups
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