Secretory Mechanisms in Cell-Mediated Cytotoxicity
Stinchcombe J, Griffiths G. Secretory Mechanisms in Cell-Mediated Cytotoxicity. Annual Review Of Cell And Developmental Biology 2007, 23: 495-517. PMID: 17506701, DOI: 10.1146/annurev.cellbio.23.090506.123521.Peer-Reviewed Original ResearchConceptsCytotoxic T lymphocytesCell-mediated cytotoxicityT cell receptorSecretory mechanismMHC class I-peptide complexesClass I-peptide complexesI-peptide complexesT lymphocytesTarget cellsTumorigenic cellsImmune systemLytic granulesCell typesLethal hitCellsMolecular basisNovel mechanismSecretory apparatusYears various studiesReceptorsTCR
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