L is for lytic granules: lysosomes that kill
Page L, Darmon A, Uellner R, Griffiths G. L is for lytic granules: lysosomes that kill. Biochimica Et Biophysica Acta 1998, 1401: 146-156. PMID: 9531970, DOI: 10.1016/s0167-4889(97)00138-9.Peer-Reviewed Original ResearchConceptsSecretory lysosomesSecretory granulesLytic granulesUnusual secretory pathwaySorting mechanismCalcium-mediated exocytosisSecretion of proteinsSorting signalHemopoietic lineagesSecretory pathwaySorting defectsSorting proteinsSecretory organellesSecretory systemRegulate secretionLytic proteinsProtein degradationSecretory cellsFibroblast lysosomesChediak-Higashi syndromeLysosomal hydrolasesLysosomesSecreted productsProteinGenetic mutations
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