Maternal α-cypermethrin and permethrin exert differential effects on fetal growth, placental morphology, and fetal neurodevelopment in mice
Elser B, Hing B, Eliasen S, Afrifa M, Meurice N, Rimi F, Chimenti M, Schulz L, Dailey M, Gibson-Corley K, Stevens H. Maternal α-cypermethrin and permethrin exert differential effects on fetal growth, placental morphology, and fetal neurodevelopment in mice. Toxicological Sciences 2025, 207: 91-108. PMID: 40517329, PMCID: PMC12448229, DOI: 10.1093/toxsci/kfaf079.Peer-Reviewed Original ResearchFetal growthGestational dayFetal developmentMaternal exposurePregnant CD1 miceGlutamate receptor signalingCorn oil vehicleType I pyrethroid permethrinFetal neurodevelopmentPlacental morphologyPlacental toxicityPlacental developmentCD1 miceExtracellular matrix remodelingOral gavageIndividual placentasOil vehicleDownregulation of genesReceptor signalingHuman studiesC-AMPNeurodevelopmentType I pyrethroidsType II pyrethroidsDorsal forebrain
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