The mutation effect reaction norm (mu‐rn) highlights environmentally dependent mutation effects and epistatic interactions
Ogbunugafor C. The mutation effect reaction norm (mu‐rn) highlights environmentally dependent mutation effects and epistatic interactions. Evolution 2022, 76: 37-48. PMID: 34989399, DOI: 10.1111/evo.14428.Peer-Reviewed Original ResearchConceptsReaction normsFitness effects of mutationsPhenotypic consequences of mutationsEvolution of antimicrobial resistanceEffects of mutationsConsequences of mutationsGenetic interactionsPopulation geneticsEpistatic interactionsPhenotypic consequencesGenetic informationMutational effectsFunction of environmental contextUnpredictability of evolutionFitness effectsMutationsAntimicrobial resistanceLayer of complexityEnvironmental contextModern SynthesisPerformance of genotypesReverse evolutionEpistasisGeneticsPublic health
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