Oxidation sensitizes TRPV2 to chemical and heat stimuli, but not mechanical stimulation
Oda M, Fujiwara Y, Ishizaki Y, Shibasaki K. Oxidation sensitizes TRPV2 to chemical and heat stimuli, but not mechanical stimulation. Biochemistry And Biophysics Reports 2021, 28: 101173. PMID: 34841092, PMCID: PMC8605382, DOI: 10.1016/j.bbrep.2021.101173.Peer-Reviewed Original ResearchTransient receptor potential vanilloid 2Response to 2-APBTransient receptor potential vanilloid 2 activationOocyte expression systemTwo-electrode voltage clamp recordingsMechanical stimulationVoltage clamp recordingsChemical ligandsOxidant chloramine TNoxious heatClamp recordingsOxidation of methionine residuesHeat stimuliTRP channelsTwo-electrodeOxidationLigandExpression systemStimulationChloramine TOocytesCell expression systemMethionine residuesMammalian cell expression systemChemical
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