2023
Localized osmotic stress activates systemic responses to N limitation in Medicago truncatula–Sinorhizobium symbiotic plants
Martin M, Pervent M, Lambert I, Colella S, Tancelin M, Severac D, Clément G, Tillard P, Frugier F, Lepetit M. Localized osmotic stress activates systemic responses to N limitation in Medicago truncatula–Sinorhizobium symbiotic plants. Frontiers In Plant Science 2023, 14: 1288070. PMID: 38053772, PMCID: PMC10694431, DOI: 10.3389/fpls.2023.1288070.Peer-Reviewed Original ResearchSymbiotic plantsNodule developmentOsmotic stressN limitationSystemic N signalingSymbiotic root nodulesPlant nitrogen demandSplit-root systemSymbiotic dinitrogen fixationN signalingTranscriptomic reprogrammingNodule senescenceRoot nodulesTarget transcriptsSucrose allocationAtmospheric dinitrogenDinitrogen fixation activityPEG treatmentEdaphic environmentFixation activityNitrogen demandDinitrogen fixationPlantsUntreated rootsN deficit
2022
Epigenetic and transcriptomic reprogramming in monocytes of severe COVID-19 patients reflects alterations in myeloid differentiation and the influence of inflammatory cytokines
Godoy-Tena G, Barmada A, Morante-Palacios O, de la Calle-Fabregat C, Martins-Ferreira R, Ferreté-Bonastre A, Ciudad L, Ruiz-Sanmartín A, Martínez-Gallo M, Ferrer R, Ruiz-Rodriguez J, Rodríguez-Ubreva J, Vento-Tormo R, Ballestar E. Epigenetic and transcriptomic reprogramming in monocytes of severe COVID-19 patients reflects alterations in myeloid differentiation and the influence of inflammatory cytokines. Genome Medicine 2022, 14: 134. PMID: 36443794, PMCID: PMC9706884, DOI: 10.1186/s13073-022-01137-4.Peer-Reviewed Original ResearchConceptsDNA methylation alterationsSevere COVID-19 patientsInterferon-related genesCOVID-19 patientsCell typesMethylation alterationsMyeloid differentiationSingle-cell transcriptomesSingle-cell transcriptomicsDNA methylation changesGene expression changesPeripheral blood monocytesImmune cell typesMethylationEPIC BeadChip arraySpecific DNA methylation alterationsTranscriptional reprogrammingDNA methylomeTranscriptomic reprogrammingDNA methylationInflammatory cytokinesMethylation changesEpigenetic alterationsBlood monocytesExpression changesBeadChip array
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply