2024
From Connectivity to Controllability: Unraveling the Brain Biomarkers of Major Depressive Disorder
Pan C, Ma Y, Wang L, Zhang Y, Wang F, Zhang X. From Connectivity to Controllability: Unraveling the Brain Biomarkers of Major Depressive Disorder. Brain Sciences 2024, 14: 509. PMID: 38790487, PMCID: PMC11119370, DOI: 10.3390/brainsci14050509.Peer-Reviewed Original ResearchMajor depressive disorderFunctional magnetic resonance imagingDepressive disorderTreatment of Major Depressive DisorderBiomarkers of major depressive disorderBrain functional networksDevelopment of precision medicine strategiesBrain regionsNetwork topology perspectiveNetwork neuroscienceBrain biomarkersBrain's abilityBrain statesPersonalized interventionsFunctional networksBrainMagnetic resonance imagingEfficacy of treatmentDisordersResonance imagingTopological perspectivePathological profileComplex dynamicsNeuroscienceLearning
2023
Tau-PET abnormality as a biomarker for Alzheimer’s disease staging and early detection: a topological perspective
Ding J, Shen C, Wang Z, Yang Y, Fakhri G, Lu J, Liang D, Zheng H, Zhou Y, Sun T, Study F. Tau-PET abnormality as a biomarker for Alzheimer’s disease staging and early detection: a topological perspective. Cerebral Cortex 2023, 33: 10649-10659. PMID: 37653600, DOI: 10.1093/cercor/bhad312.Peer-Reviewed Original ResearchConceptsStandardized uptake value ratioMild cognitive impairmentBrain regionsCognitive impairmentPositron emission tomographyMedial temporal lobeAlzheimer's diseaseVisual-related regionsTopological perspectiveTau positron emission tomographyMode networkTau PET imagingTopological featuresIndependent data cohortsTemporal lobeConnection strengthExtract topological featuresTau networksAbnormal networkProgression of Alzheimer's diseaseAbnormal protein accumulation
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