Evaluation of tumor immune microenvironment in Hispanic and African American breast cancer.
Hsu R, Deshmukh S, Rallos E, Al-zubeidy B, Martynova A, Stewart D, Jayachandran P, Spicer D, Wu S, Xiu J, Sledge G, Gandhi S, Chumsri S, Leone J, Mahtani R, Sandoval Leon A, Lustberg M, Roussos Torres E. Evaluation of tumor immune microenvironment in Hispanic and African American breast cancer. Journal Of Clinical Oncology 2025, 43: 1051-1051. DOI: 10.1200/jco.2025.43.16_suppl.1051.Peer-Reviewed Original ResearchTumor immune microenvironmentPrimary breast cancerCD8+ T cellsBreast cancerT cellsPD-L1Non-Hispanic whitesOverall survivalImmune microenvironmentIFN-gammaInflamed tumor immune microenvironmentAdvanced-stage breast cancerReal-world overall survivalEarly-stage BCImmune cell fractionsM2-like macrophagesMann-Whitney U testAfrican American breast cancerKaplan-Meier estimatesAA tumorsHER2+TMB-highPBC casesBC patientsImmune cells
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