A Multi-Modal and Generalizable Nanogold Tag for Cryo-Electron Tomography in Intact Cells
Young L, Sherrard A, Shaikh F, Zhou H, Hutchings J, Rosen M, Giraldez A, Villa E. A Multi-Modal and Generalizable Nanogold Tag for Cryo-Electron Tomography in Intact Cells. Structural Dynamics 2025, 12: a166-a166. DOI: 10.1063/4.0000475.Peer-Reviewed Original ResearchCryo-electron tomographyPer-particle basisSpatial resolutionSubtomogram analysisCryo-electronAssociated with heterochromatinHistone variantsStructure-function-relationshipsRibosomal targetMinimal perturbationIntact cellsTagging methodHomologous moleculesHeterochromatinTarget macromoleculesNative environmentGold nanoparticlesSubtomogramPerturbation
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