2020
The NBDY Microprotein Regulates Cellular RNA Decapping
Na Z, Luo Y, Schofield JA, Smelyansky S, Khitun A, Muthukumar S, Valkov E, Simon MD, Slavoff SA. The NBDY Microprotein Regulates Cellular RNA Decapping. Biochemistry 2020, 59: 4131-4142. PMID: 33059440, PMCID: PMC7682656, DOI: 10.1021/acs.biochem.0c00672.Peer-Reviewed Original ResearchConceptsP-bodiesNonsense-mediated decay factorsKO cellsSmall open reading framesCytoplasmic ribonucleoprotein granulesOpen reading frameSubstrate transcriptsCellular transcriptomeRibonucleoprotein granulesTarget transcriptsRNA stabilityKnockout cellsUTR lengthReading frameGlobal profilingProteogenomic identificationMacromolecular complexesHuman RNACellular RNACytoplasmic RNAGene stabilityAmino acidsCell growthMicroproteinsTranscripts
1993
Domain 5 interacts with domain 6 and influences the second transesterification reaction of group II intron self-splicing
Dib-Hajj S, Boulanger S, Hebbar S, Peebles C, Franzen J, Perlman P. Domain 5 interacts with domain 6 and influences the second transesterification reaction of group II intron self-splicing. Nucleic Acids Research 1993, 21: 1797-1804. PMID: 8493099, PMCID: PMC309417, DOI: 10.1093/nar/21.8.1797.Peer-Reviewed Original ResearchConceptsSplice site useSplice site utilizationSplice siteDomain 5Yeast mitochondrial DNAGroup II intronsSecond transesterification reactionSubstrate transcriptsCoxI geneSplicing occursMitochondrial DNARNA moleculesDomain 6RNAExonsD5 RNASite utilizationTranscriptsKey roleIntronsBranchingSite residentsSite useGenesSites
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