2011
Peripheral T-cell lymphoma
Foss FM, Zinzani PL, Vose JM, Gascoyne RD, Rosen ST, Tobinai K. Peripheral T-cell lymphoma. Blood 2011, 117: 6756-6767. PMID: 21493798, DOI: 10.1182/blood-2010-05-231548.Peer-Reviewed Original ResearchConceptsPeripheral T-cell lymphomaT-cell lymphomaStandard chemotherapeutic regimensBest treatment strategyMore effective therapiesHistone deacetylase inhibitorsWorld Health OrganizationAbundance of drugsAggressive diseaseChemotherapeutic regimensPoor outcomeTreatment optionsClinical trialsEffective therapyTreatment strategiesTherapeutic approachesPrognostic issuesDeacetylase inhibitorsLymphoma classificationMonoclonal antibodiesGene expression profilingHeterogeneous groupHealth OrganizationProteasome inhibitorsDisease biology
2008
The efficacy of combination therapy using adeno-associated virus—interferon β and trichostatin A in vitro and in a murine model of neuroblastoma
Hamner J, Sims T, Cutshaw A, Dickson P, Rosati S, McGee M, Ng C, Davidoff A. The efficacy of combination therapy using adeno-associated virus—interferon β and trichostatin A in vitro and in a murine model of neuroblastoma. Journal Of Pediatric Surgery 2008, 43: 177-183. PMID: 18206478, DOI: 10.1016/j.jpedsurg.2007.09.048.Peer-Reviewed Original ResearchMeSH KeywordsAdenoviridaeAnimalsBlotting, WesternCell Line, TumorCombined Modality TherapyDisease Models, AnimalGenetic TherapyHumansHydroxamic AcidsIn Vitro TechniquesInterferon-betaMaleMiceMice, SCIDNeuroblastomaProbabilityRandom AllocationSensitivity and SpecificityXenograft Model Antitumor AssaysConceptsSevere combined immune deficiencyTrichostatin AHIFN-betaIFN-betaRetroperitoneal neuroblastomaMurine modelIncreased expression of p21(WAF1Interferon-betaEfficacy of combination therapyMurine model of neuroblastomaCombination-treated tumorsStandard chemotherapeutic regimensCells treated with trichostatin ATrichostatin A in vitroCombined immune deficiencyGene therapy approachesIn vivo experimentsModel of neuroblastomaTreated with vehicleCell linesNeuroblastoma cells in vitroWestern blottingHistone deacetylase inhibitorsHuman neuroblastoma cells in vitroExpression of p21(WAF1
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply