OR24-01 Time to Sperm Suppression With Daily Transdermal Use of Nestorone and Testosterone Combination Gel for Male Contraception Is Faster Than Expected
Gross D, Wang C, Page S, Sitruk-Ware R, Creinin M, Anderson R, Edelman A, Turok D, Kinuthia J, Vinay J, Barnhart K, Danielsson K, Mhlanga F, Fitzgerald C, Meriggiola C, Archer D, Lazorwitz A, Amory J, Swerdloff R, Bremner W, Lee M, Kroopnick J, Blithe D. OR24-01 Time to Sperm Suppression With Daily Transdermal Use of Nestorone and Testosterone Combination Gel for Male Contraception Is Faster Than Expected. Journal Of The Endocrine Society 2024, 8: bvae163.2435. PMCID: PMC12047133, DOI: 10.1210/jendso/bvae163.2435.Peer-Reviewed Original ResearchSperm suppressionWeek 8Male contraceptionCombination gelPhase IIb clinical trialDaily self-administrationTime to suppressionWeeks of treatmentFollow-up visitWeek 5Reversible male contraceptive methodsSperm concentration assessmentMale contraceptive methodsDaily skin applicationsSpermatogenic suppressionContraceptive efficacyHormone regimensEffective contraceptionHormonal agentsSelf-AdministrationInitial treatmentSegesterone acetateCo-administrationGel applicationTransdermal use
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