Novel insights into astrocyte-mediated signaling of proliferation, invasion and tumor immune microenvironment in glioblastoma
Zhang H, Zhou Y, Cui B, Liu Z, Shen H. Novel insights into astrocyte-mediated signaling of proliferation, invasion and tumor immune microenvironment in glioblastoma. Biomedicine & Pharmacotherapy 2020, 126: 110086. PMID: 32172060, DOI: 10.1016/j.biopha.2020.110086.Peer-Reviewed Original ResearchConceptsTumor-associated astrocytesTumor cellsChemoradiotherapy resistanceResistance of tumor cellsTumor immune microenvironmentReactive astrocytesSuppress immune responsesSignals of proliferationCentral nervous systemPrognosis of glioblastomaImmunosuppressive regulationDismal prognosisImmune microenvironmentTumor progressionAggressive cancerClinical studiesGlioblastoma microenvironmentImmune responseGlioblastomaGlioblastoma treatmentTumorFunctions of reactive astrocytesActivated astrocytesNervous systemCell interactions
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