2019
Two well-differentiated pancreatic neuroendocrine tumor mouse models
Wong C, Tang LH, Davidson C, Vosburgh E, Chen W, Foran DJ, Notterman DA, Levine AJ, Xu EY. Two well-differentiated pancreatic neuroendocrine tumor mouse models. Cell Death & Differentiation 2019, 27: 269-283. PMID: 31160716, PMCID: PMC7206057, DOI: 10.1038/s41418-019-0355-0.Peer-Reviewed Original ResearchConceptsMultiple endocrine neoplasia type 1Neuroendocrine tumorsMouse modelShort latencyPI3K/Akt/mTORPancreatic neuroendocrine tumorsPituitary neuroendocrine tumorsTumor mouse modelAkt/mTORMTOR inhibitor rapamycinCre-loxP systemNeuroendocrine cancerProlonged survivalProlonged latencyMEN1 patientsMouse insulin 1 promoterSame miceMen1 lossTherapeutic opportunitiesType 1Genetic syndromesPTEN lossEarly onsetTumorsTumor development
2017
Customized Recommendations and Reminder Text Messages for Automated, Computer-Based Treatment During Methadone
Moore BA, Buono FD, Printz DMB, Lloyd DP, Fiellin DA, Cutter CJ, Schottenfeld RS, Barry DT. Customized Recommendations and Reminder Text Messages for Automated, Computer-Based Treatment During Methadone. Experimental And Clinical Psychopharmacology 2017, 25: 485-495. PMID: 29251978, PMCID: PMC5737744, DOI: 10.1037/pha0000149.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyPatient engagementReminder messagesPreliminary efficacy findingsMethadone-maintained patientsSubstance use disordersIllicit drug useRandomized trialsEfficacy findingsMethadone maintenanceUse disordersPatient useDrug useSystem functionBehavioral therapyComputer-based interventionsPatientsShort latencyTotal call timeTrial 2Trial 1Line callsSelf-management systemCall timeTotal contact timeOccupational lung diseases: from old and novel exposures to effective preventive strategies
Cullinan P, Muñoz X, Suojalehto H, Agius R, Jindal S, Sigsgaard T, Blomberg A, Charpin D, Annesi-Maesano I, Gulati M, Kim Y, Frank AL, Akgün M, Fishwick D, de la Hoz RE, Moitra S. Occupational lung diseases: from old and novel exposures to effective preventive strategies. The Lancet Respiratory Medicine 2017, 5: 445-455. PMID: 28089118, DOI: 10.1016/s2213-2600(16)30424-6.Peer-Reviewed Original ResearchConceptsOccupational lung diseaseLung diseaseCommon occupational lung diseaseNon-communicable lung diseasesWork-related asthmaEffective preventive strategiesMalignant lung diseaseOccupational exposurePreventive strategiesRespiratory diseaseAsthmaControl measuresDiseaseNovel exposureShort latencyGlobal causeIncidenceExposureHeavy burdenBurdenRiskManagement of workersCauseProximal causeRapid economic transition
2009
BrafV600E cooperates with Pten loss to induce metastatic melanoma
Dankort D, Curley DP, Cartlidge RA, Nelson B, Karnezis AN, Damsky Jr W, You MJ, DePinho RA, McMahon M, Bosenberg M. BrafV600E cooperates with Pten loss to induce metastatic melanoma. Nature Genetics 2009, 41: 544-552. PMID: 19282848, PMCID: PMC2705918, DOI: 10.1038/ng.356.Peer-Reviewed Original Research
1996
Burst-firing activity of presumed 5-HT neurones of the rat dorsal raphe nucleus: electrophysiological analysis by antidromic stimulation
Hajós M, Sharp T. Burst-firing activity of presumed 5-HT neurones of the rat dorsal raphe nucleus: electrophysiological analysis by antidromic stimulation. Brain Research 1996, 740: 162-168. PMID: 8973810, DOI: 10.1016/s0006-8993(96)00869-4.Peer-Reviewed Original ResearchConceptsDorsal raphe nucleusAntidromic spikesAntidromic stimulationRaphe nucleusRat dorsal raphe nucleusBurst-firing activityRaphe nuclei projectAntidromic spike latencyDorsal raphe nucleus projectMedial forebrain bundleForebrain bundleNuclei projectRaphe neuronesElectrical stimulationNeurones projectSpike latencyAction potentialsSpike doubletsNeuronesShort latencyElectrophysiological analysisStimulationForebrainAxons
1983
Latency to detection of first pain
Campbell J, LaMotte R. Latency to detection of first pain. Brain Research 1983, 266: 203-208. PMID: 6871657, DOI: 10.1016/0006-8993(83)90650-9.Peer-Reviewed Original ResearchConceptsFirst painFirst sensationShort-latency responsesQuality of sensationDistal forearmPrimary afferentsPain sensationConduction velocityThenar eminenceGlabrous handHeat stimuliPainLatency responsesMedian response latencyShort latencyDistal armSensationResponse latencyStimuliSubjectsLatencyAfferentsArmForearmMs
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