2012
Cigarette Smoking Predicts Differential Benefit from Naltrexone for Alcohol Dependence
Fucito LM, Park A, Gulliver SB, Mattson ME, Gueorguieva RV, O'Malley SS. Cigarette Smoking Predicts Differential Benefit from Naltrexone for Alcohol Dependence. Biological Psychiatry 2012, 72: 832-838. PMID: 22541040, PMCID: PMC3410039, DOI: 10.1016/j.biopsych.2012.03.023.Peer-Reviewed Original ResearchConceptsCigarette smokingAlcohol dependenceBehavioral interventionsAlcohol-dependent smokersCombination of medicationsBaseline demographic differencesPoor treatment outcomesPoor treatment responseDrinking outcomesBetter drinking outcomesSevere alcohol dependenceAlcohol-dependent individualsCigarette intakeAlcohol use outcomesMedical managementPharmacological treatmentTreatment outcomesTreatment responseSmokingSmokersCOMBINE StudyAlcoholism typologyDrinking-related variablesTreatment assignmentNonsmokers
2001
Naltrexone in the Treatment of Alcohol Dependence
Krystal J, Cramer J, Krol W, Kirk G, Rosenheck R. Naltrexone in the Treatment of Alcohol Dependence. New England Journal Of Medicine 2001, 345: 1734-1739. PMID: 11742047, DOI: 10.1056/nejmoa011127.Peer-Reviewed Original ResearchConceptsMonths of placeboSevere alcohol dependenceAlcohol dependencePlacebo-controlled evaluationUse of naltrexoneOpiate receptor antagonistTreatment of menSignificant differencesPercentage of daysStudy medicationNaltrexone groupPlacebo groupNumber of drinksAlcoholics Anonymous meetingsPsychosocial treatmentsNaltrexoneDrug AdministrationPatientsMonthsIndividual counselingNumber of daysPlaceboTreatmentWeeksDays
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