2013
Transient overexpression of TGFBR3 induces apoptosis in human nasopharyngeal carcinoma CNE-2Z cells
Zheng F, He K, Li X, Zhao D, Sun F, Zhang Y, Nie D, Li X, Chu W, Sun Y, Lu Y. Transient overexpression of TGFBR3 induces apoptosis in human nasopharyngeal carcinoma CNE-2Z cells. Bioscience Reports 2013, 33: e00029. PMID: 23387308, PMCID: PMC3596095, DOI: 10.1042/bsr20120047.Peer-Reviewed Original ResearchConceptsCaspase 3 activityTransient overexpressionBcl-2P-BadCNE-2Z cellsApoptosis-inducing factorCNE-2ZExpression of apoptosis-related proteinsPro-apoptotic BadCaspase 3 pathwayApoptosis-related proteinsCaspase 3 activity kitXIAP proteinBax proteinTime-dependent mannerInduce apoptosisCaspaseForced expressionReduced viabilityPlasmid DNAApoptosisXIAPTGFBR3 overexpressionProteinNasopharyngeal carcinoma CNE-2Z cells
2003
Assessment of Insulin-Like Growth Factors and Mutagen Sensitivity as Predictors of Lung Cancer Risk
Wu X, Yu H, Makan N, Spitz M. Assessment of Insulin-Like Growth Factors and Mutagen Sensitivity as Predictors of Lung Cancer Risk. Methods In Molecular Medicine 2003, 75: 279-287. PMID: 12407747, DOI: 10.1385/1-59259-324-0:279.Peer-Reviewed Original ResearchMeSH Keywords7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxideBleomycinChromatidsChromosome AberrationsEnzyme-Linked Immunosorbent AssayHumansInsulin-Like Growth Factor Binding Protein 3Insulin-Like Growth Factor IInsulin-Like Growth Factor IILung NeoplasmsLymphocytesMutagenicity TestsMutagensPredictive Value of TestsRisk FactorsConceptsInsulin-like growth factorSignal transduction pathwaysGrowth factorCell cycle progressionCell membrane receptorsTransduction pathwaysBcl proteinsMAP kinaseLung cancer cellsIGF-1 receptorCell deathMembrane receptorsS phaseAntiproliferative moleculesBinding of IGFBax proteinCell proliferationLung cancer riskImportant functionsProteinCancer cellsCyclin D1Retinoic acidTypes of peptidesMitogenic action
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