2024
Spatially Informed Gene Signatures for Response to Immunotherapy in Melanoma.
Aung T, Warrell J, Martinez-Morilla S, Gavrielatou N, Vathiotis I, Yaghoobi V, Kluger H, Gerstein M, Rimm D. Spatially Informed Gene Signatures for Response to Immunotherapy in Melanoma. Clinical Cancer Research 2024, 30: 3520-3532. PMID: 38837895, PMCID: PMC11326985, DOI: 10.1158/1078-0432.ccr-23-3932.Peer-Reviewed Original ResearchGene signatureResistance to immunotherapyResponse to immunotherapyPrediction of treatment outcomeResistant to treatmentAccurate prediction of treatment outcomePredictive of responseImmunotherapy outcomesMelanoma patientsMelanoma specimensValidation cohortPatient stratificationDiscovery cohortTreatment outcomesImmunotherapyMelanomaTumorPatientsCohortS100BOutcomesGene expression dataGenesCD68+macrophagesExpression data
2019
Effects of Antipsychotic Treatment on S100B and Oxidative Stress in Patients with Schizophrenia
Wang X, Bian Y, Liu L, Wu Y, Yang F, Li X, Han X, Tian L, Luo X, Chen S, Wang Z, Tan Y, Li Y. Effects of Antipsychotic Treatment on S100B and Oxidative Stress in Patients with Schizophrenia. Global Clinical And Translational Research 2019, 120-127. DOI: 10.36316/gcatr.01.0018.Peer-Reviewed Original ResearchDrug-naive patientsLevels of S100BFirst-episode drug-naive patientsAntipsychotic treatmentTotal oxidative statusAcute-phase schizophreniaLevels of malondialdehydeAcute phasePatient groupOxidative stressAcute phase patientsDSM-IV diagnostic criteriaAntipsychotic treatment effectsPANSS negative scoresNegative Syndrome ScaleRandom-effects modelSerum S100BPhase patientsSerum levelsDiagnostic criteriaPatientsSyndrome ScaleS100BRisperidoneOxidative status
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