Leptin and the Perioperative Neuroendocrinological Stress Response1
Kain Z, Zimolo Z, Heninger G. Leptin and the Perioperative Neuroendocrinological Stress Response1. The Journal Of Clinical Endocrinology & Metabolism 1999, 84: 2438-2442. PMID: 10404818, DOI: 10.1210/jcem.84.7.5850.Peer-Reviewed Original ResearchConceptsSurgical stressLeptin decreaseHigh-dose opioid techniqueCortisol increasePhase IHigh-dose fentanylSurgical stress responseTotal abdominal hysterectomyCardiac surgery patientsBaseline 2 hPossible adverse outcomesBaseline 24 hPhase IIAcute stress responseDose fentanylAbdominal hysterectomyPostoperative morbiditySurgery patientsHysterectomy patientsLeptin levelsAnesthetic techniqueAdverse outcomesAdrenocortical axisCardiac patientsNeuroendocrine hormones
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