Ligand Modulates Cross-Coupling between Riboswitch Folding and Transcriptional Pausing
Widom J, Nedialkov Y, Rai V, Hayes R, Brooks C, Artsimovitch I, Walter N. Ligand Modulates Cross-Coupling between Riboswitch Folding and Transcriptional Pausing. Molecular Cell 2018, 72: 541-552.e6. PMID: 30388413, PMCID: PMC6565381, DOI: 10.1016/j.molcel.2018.08.046.Peer-Reviewed Original ResearchMeSH KeywordsAptamers, NucleotideDNA-Directed RNA PolymerasesEscherichia coliEscherichia coli ProteinsFluorescence Resonance Energy TransferGene Expression Regulation, BacterialLigandsNucleic Acid ConformationNucleoside QProtein FoldingRiboswitchRNA FoldingRNA, BacterialSingle Molecule ImagingTranscription, GeneticConceptsCellular RNA transcriptsBacterial gene expressionRNA polymerase pausingCo-transcriptional foldingTranscriptional pausingTranscription machineryNascent RNAPolymerase pausingRiboswitch foldingRiboswitchRNA transcriptsGene expressionNative foldPhysiological cuesRNAPFunctional contextPausingFoldingNumerous classesAntibacterial drugsPreQTranscriptsRNAMachineryPseudoknots
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply